王璕 博士 副研究员 硕士生导师

教育经历

2003-2007 深圳大学 mgm4858am美高梅集团 理学学士

2007-2014 韩国忠南大学 生命科学与生物技术学院 硕博连读 理学博士

科研与工作经历

2018-至今 mgm4858am美高梅集团生科院 副研究员

2015-2018 mgm4858am美高梅集团生科院 博士后

研究方向简介

1. 合成生物学、微生物代谢工程

2. 大肠杆菌分子遗传学

代表性研究成果

学术论文

1.         Wang X, Abishek NMP, Jeon HJ, Lee Y, He J, Adhya S, Lim HM. (2019) Processing generates 3’ ends of RNA masking transcription termination events in prokaryotes. P Natl Acad Sci USA (in press)

2.         Wang X, Jeon HJ, Abishek NMP, He J, Lim HM. (2018) Visualization of RNA 3’ ends in Escherichia coli using 3’ RACE combined with primer extension. Bio-protocol 8. doi: 10.21769/BioProtoc.2752

3.         Wang X, Z. Li, X. Li, H.L. Qian, X. Cai, X.F. Li & J. He, (2016) Poly-beta-hydroxybutyrate metabolism is unrelated to the sporulation and parasporal crystal protein formation in Bacillus thuringiensis. Front Microbiol 7:836. doi: 10.3389/fmicb.2016.00836

4.         Wang X, Ji SC, Lim HM. (2015) Two-level inhibition of galK expression by Spot 42: Degradation of mRNA mK2 and enhanced transcription termination before the galK gene. P Natl Acad Sci USA 112: 7581-7586. doi: 10.1073/pnas.1424683112

5.         Wang X, Ji SC, Yun SH, Jeon HJ, Kim SW, Lim HM. (2014). Expression of each cistron in the gal operon can be regulated by transcription termination and generation of a galK-Specific mRNA, mK2. J Bacteriol 196: 2598-2606. doi: 10.1128/JB.01577-14

6.         Ji, SC, Wang X, Yun, SH, Jeon, HJ, Lee HJ, Lim, HM. (2011) In vivo transcription dynamics of the galactose operon: a study on the promoter transition from P1 to P2 at onset of stationary phase. PLoS ONE, 6(3): e17646. doi: 10.1371/journal.pone.0017646

7.         Ji, SC, Wang X, Jeon, HJ, Yun, SH, Lee, HJ, Lim, HM. (2010) Quantification of the galactose-operon mRNAs 5 bases different in their 5'-ends. BMB Rep, 43, 474-479. PMID: 20663408

8.         Zheng C, Ma Y, Wang X, Xie Y, Ali MK and He J. (2015) Functional analysis of the sporulation-specific diadenylate cyclase CdaS in Bacillus thuringiensis. Front Microbiol 6: 908. doi.org/10.3389/fmicb.2015.00908

9.         Zhang S, Hu Y, Fan Q, Wang X, He J. (2015) Two-component system YvqEC-dependent bacterial resistance against vancomycin in Bacillus thuringiensis. Antonie van Leeuwenhoek. 108(2): 365-376. doi: 10.1007/s10482-015-0489-0

10.     Zhang SM, Li XF, Wang X, Li Z, He J. (2016) The two-component signal transduction system YvcPQ regulates the bacterial resistance to bacitracin in Bacillus thuringiensis. Archives of Microbiology, 198:773-784. doi: 10.1007/s00203-016-1239-z.

11.     Yun, SH, Ji, SC, Jeon, HJ, Wang X, Kim, SW, Bak, G., Lee, Y, Lim, HM. (2012) The CnuK9E H-NS complex antagonizes DNA binding of DicA and Leads to temperature-dependent filamentous growth in E. coli. PLoS ONE, 7(9): e45236. doi: 10.1371/journal.pone.0045236

12.     Yun, SH, Ji, SC, Jeon, HJ, Wang X, Lee, Y, Choi, BS, Lim, HM. (2012) A mutational study of Cnu reveals attractive forces between Cnu and H-NS. Mol Cells. 33(2): 211-216. doi: 10.1007/s10059-012-0006-5

研究生招生专业

生物工程，微生物学

联系方式

电子邮箱：wangxun@mail.hzau.edu.cn

办公地点：第一综合楼A401、农业微生物学国家重点实验室A311