李友国 　博士　教授 博士生导师

教育经历

1984-1988　  武汉大学生物系 细胞生物学，学士学位

1988-1991　  武汉大学 生物系细胞生物学，硕士学位

1997-2000　  mgm4858am美高梅集团 生科院，博士学位

科研与学术工作经历

1991-1994　  mgm4858am美高梅集团土壤农业化学系，微生物学教研室任教

1994-2001　  mgm4858am美高梅集团生科院，微生物学教研室任教，2000年获微生物学博士学位，聘为副教授

2001-2001　  荷兰Wageningen大学微生物分子生态学实验室，访问学者

2002-2005　  英国East Anglia大学生命科学院，博士后研究

2005-现在　  农业微生物国家重点实验室PI，2007年聘为教授和博士生导师

研究方向

根瘤菌共生固氮体系的分子机理与应用

利用华癸根瘤菌-紫云英特色模式体系，研究共生双方调控类菌体分化、固氮及衰老的互作机制

开展大豆根瘤菌固氮及菌植互作研究，为增强竞争结瘤、提高固氮效率和大豆固氮育种提供科学依据

进行大豆和紫云英根瘤菌的遗传改良、整合利用PGPR、微量元素、激素等，建立与我国土壤及豆科宿主匹配的复合根瘤菌制剂应用技术

代表性研究成果

论文

1. Jianyun Wang, Zaiyong Si, Fang Li, Xiaobo Xiong, Lei Lei, Fuli Xie, Dasong Chen, Yixing Li*, Youguo Li* (2015). A purple acid phosphatase plays a role in nodule formation and nitrogen fixation in Astragalus sinicus. Plant Molecular Biology, 88 (6): 515-29.

2. Lei, L., L. Chen, X. Shi, Y. Li, J. Wang, D. Chen, F. Xie and Y. Li* (2014). A nodule-specific lipid transfer protein AsE246 participates in transport of plant-synthesized lipids to symbiosome membrane and is essential for nodule organogenesis in Chinese milk vetch. Plant Physiol 164 (2): 1045-1058.

3. Shanming Wang, Baohai Hao, Jiarui Li, Jieli Peng, Fuli Xie, Xinyin Zhao, Christian Frech, Nansheng Chen*, Binguang Ma*, Youguo Li* (2014). Whole-genome sequencing of Mesorhizobium huakuii 7653R provides molecular insights into host specificity and symbiosis island dynamics. BMC Genomics, 15: 440.

4. Peng, J., B. Hao, L. Liu, S. Wang, B. Ma, Y. Yang, F. Xie and Y. Li* (2014). RNA-Seq and Microarrays Analyses Reveal Global Differential Transcriptomes of Mesorhizobium huakuii 7653R between Bacteroids and Free-Living Cells. PLoS One 9 (4): e93626.

5. Yixing Li, Lei Zhou, Youguo Li*, Dasong Chen, Xuejuan Tan, Lei Lei and Junchu Zhou* (2008). A nodule-specific plant cysteine proteinase, AsNODF32, is involved in nodule senescence and nitrogen fixation activity of the green manure legume Astragalus sinicus. New Phytologist, 180: 185-192.

6. Jiang Ke Yang, Tian Ying Yuan, Wei Tao Zhang, Jun Chu Zhou, You Guo Li* (2008). Polyphasic characterization of mung bean (Vigna radiata L.) rhizobia from different geographical regions of China. Soil Biology & Biochemistry, 40: 1681-1688.

7. Jonathan D. Todd, Rachel Rogers, You Guo Li, Margaret Wexler, Philip L. Bond, Lei Sun, Andrew R. J. Curson, Gill Malin, Michael Steinke, Andrew W. B. Johnston (2007). Structural and Regulatory Genes Required to Make the Gas Dimethyl Sulfide in Bacteria. Science, Vol. 315: 666-669.

8. Y. Li, M. Wexler, D. J. Richardson, P. L. Bond and A. W. B. Johnston (2005). Screening a Wide Host-range, Waste-water Metagenomic Library in Tryptophan Auxotrophs of Rhizobium leguminosarum and of Escherichia coli Reveals Different Classes of Cloned trp Genes. Environmental Microbiology, 7(12), 1927-1936.

9. A.W.B.Johnston, Youguo Li and Lesley Ogilvie (2005). Metagenomic Marine Nitrogen Fixation - Feast or Famine? Trends in Microbiology, 13(9): 416-420.

主讲课程

普通微生物学、固氮生物学、近代生物学研究技术

研究生招生专业

微生物学

联系方式

mgm4858am美高梅集团

农业微生物学国家重点实验室A509

湖北省武汉市洪山区狮子山街一号邮编：430070

电话：15807157676

Email: youguoli@mail.hzau.edu.cn