袁猛 中共党员 博士 教授 博士生导师
国家自然科学基金委优秀青年科学基金获得者
国家自然科学基金委“绿色超级稻生物学”创新群体核心成员
教育经历
1999-2003 mgm4858am美高梅集团 园艺林学学院 林学专业 农学学士学位
2003-2010 mgm4858am美高梅集团 mgm4858am美高梅集团 生物化学与分子生物学专业 理学博士学位
科研与学术工作经历
2011.01-2012.12 mgm4858am美高梅集团 讲师
2013.01-2018.08 mgm4858am美高梅集团 副教授
2016.11-2017.12 美国杜克大学 访问学者
2018.09-至今 mgm4858am美高梅集团 教授
2011.01-至今 作物遗传改良国家重点实验室固定研究人员
研究方向
整合遗传学、生物化学、分子生物学、生物信息学和分子植物病理学的知识和技术，开展水稻抗病基因挖掘、功能和调控机制研究工作。
代表性研究成果
论文
1. Cao J, Chu C, Zhang M, He L, Qin L, Li X, Yuan M (2020) Different cell wall-degradation ability leads to tissue-specificity between Xanthomonas oryzae pv. oryzae and Xanthomonas oryzae pv. oryzicola. Pathogens. 9:187.
2. Ke Y, Yuan M, Liu H, Hui S, Qin X, Chen J, Zhang Q, Li X, Xiao J, Zhang Q, Wang S (2020) The versatile functions of OsALDH2B1 provide a genic basis for growth-defense trade-offs in rice. Proc Natl Acad Sci USA. 117:3867-3873.
3. Yoo H#, Greene GH#, Yuan M#, Xu G, Burton D, Liu L, Marqués J, Dong X (2020) Translational regulation of metabolic dynamics during effector-triggered immunity. Mol Plant. 13:88-98. (co-first author)
4. Cao J, Zhang M, Zhu M, He L, Xiao J, Li X, Yuan M (2020) Autophagy-like cell death regulates hydrogen peroxide and calcium ion distribution in Xa3/Xa26-mediated resistance to Xanthomonas oryzae pv. oryzae. Int J Mol Sci. 21:194.
5. Tian J, Xu G, Yuan M (2019) Precise editing enables crop broad-spectrum resistance. Mol Plant. 12:1542-1544.
6. Zhang M, Wang S, Yuan M (2019) An update on molecular mechanism of disease resistance genes and their application for genetic improvement of rice. Mol Breeding. 39: 154.
7. Hui S, Liu H, Zhang M, Chen D, Li Q, Tian J, Xiao J, Li X, Wang S, Yuan M (2019) The host basal transcription factor IIA subunits coordinate for facilitating infection of TALEs-carrying bacterial pathogens in rice. Plant Sci. 284: 48-56.
8. Hui S, Shi Y, Tian J, Wang L, Li Y, Wang S, Yuan M (2019) TALE-carrying bacterial pathogens trap host nuclear import receptors for facilitating infection of rice. Mol Plant Pathol. 20: 519-532.
9. Huang R, Li Y, Tang G, Hui S, Yang Z, Zhao J, Liu H, Cao J, Yuan M (2018) Dynamic phytohormone profiling of rice upon rice black-streaked dwarf virus invasion. J Plant Physiol. 228: 92-100.
10. Xu G#, Yuan M#, Ai C, Liu L, Zhuang E, Karapetyan S, Wang S, Dong X (2017) uORF-mediated translation allows engineered plant disease resistance without fitness costs. Nature. 545: 491-494. (co-first author)
11. Huang R, Hui S, Zhang M, Li P, Xiao J, Li X, Yuan M, Wang S (2017) A conserved basal transcription factor is required for the function of diverse TAL effectors in multiple plant hosts. Front Plant Sci. 8: 1919.
12. Ke Y, Hui S, Yuan M (2017) Xanthomonas oryzae pv. oryzae inoculation and growth rate on rice by leaf clipping method. Bio-protocol. 7: e2568.
13. Yuan M, Ke Y, Huang R, Ma L, Yang Z, Chu Z, Xiao J, Li X, Wang S (2016) A host basal transcription factor is a key component for infection of rice by TALE-carrying bacteria. Elife. 5: e19605. (co-corresponding author).
14. Su J, Zou X, Huang J, Bai T, Liu S, Yuan M, Chou SH, He YW, Wang H, He J (2016) DgcA, a diguanylate cyclase from Xanthomonas oryzae pv. oryzae regulates bacterial pathogenicity on rice. Sci Rep. 6: 25978.
15. Xie W, Wang G, Yuan M, Yao W, Lyu K, Zhao H, Yang M, Li P, Zhang X, Yuan J, Wang Q, Liu F, Dong H, Zhang L, Li X, Meng X, Zhang W, Xiong L, He Y, Wang S, Yu S, Xu C, Luo J, Li X, Xiao J, Lian X, Zhang Q (2015) Breeding signatures of rice improvement revealed by a genomic variation map from a large germplasm collection. Proc Natl Acad Sci USA. 112: E5411-9.
16. Yuan M, Zhao J, Huang R, Li X, Xiao J, Wang S (2014) Rice MtN3/saliva/SWEET gene family: evolution, expression profiling, and sugar transport. J Integr Plant Biol. 56: 559-570.
17. Zhou Y, Liu L, Huang W, Yuan M, Zhou F, Li X, Lin Y (2014) Overexpression of OsSWEET5 in rice causes growth retardation and precocious senescence. PLoS One. 9: e94210.
18. Yuan M, Wang S (2013) Rice MtN3/Saliva/SWEET family genes and their homologues in cellular organisms. Mol Plant. 6: 665-674.
19. Liu Q, Yuan M, Zhou Y, Li X, Xiao J, Wang S (2011) A paralog of the MtN3/saliva family recessively confers race-specific resistance to Xanthomonas oryzae in rice. Plant Cell Environ. 34: 1958-1969.
20. Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biology. 11: 69.
21. Yuan M, Chu Z, Li X, Xu C, Wang S (2010) The bacterial pathogen Xanthomonas oryzae overcomes rice defenses by regulating host copper redistribution. Plant Cell 22: 3164-3176.
22. Yuan M, Chu Z, Li X, Xu C, Wang S (2009) Pathogen-induced expressional loss of function is the key factor in race-specific bacterial resistance conferred by a recessive R gene xa13 in rice. Plant Cell Physiol. 50: 947-955.
23. Chu Z, Yuan M, Yao J, Ge X, Yuan B, Xu C, Li X, Fu B, Li Z, Bennetzen JL, Zhang Q, Wang S (2006) Promoter mutations of an essential gene for pollen development result in disease resistance in rice. Genes Dev. 20: 1250-1255.
24. Wang G, Ding X, Yuan M, Qiu D, Li X, Xu C, Wang S (2006) Dual function of rice OsDR8 gene in disease resistance and thiamine accumulation. Plant Mol Biol. 60: 437-449.
授权专利
ZL201010595883.7，ZL200910063141.7，ZL200910063051.8，ZL200510018674.5。
主讲课程
分子克隆技术、生物信息学（国家精品资源共享课、MOOC）
研究生招生专业
生物化学与分子生物学
联系方式
实验室电话：027-87281812
电子邮箱：myuan@mail.hzau.edu.cn
办公地点：作物遗传改良国家重点实验室A508
实验室介绍及网址：
基因组研究与水稻遗传改良团队抗病课题组
