博士 教授、博导

教育经历

2007.09-2010.12

中国农业大学

作物遗传育种系

博士

2004.09-2007.07

中国农业大学

作物遗传育种系

硕士

2000.09-2004.07

中国农业大学

作物遗传育种系

学士

工作经历：

2016.08-现在

mgm4858am美高梅集团

mgm4858am美高梅集团

教授

2013.01-2016.07

明尼苏达大学双城校区

植物生物学系

博士后

2011.01-2013.01

伊利诺伊大学香槟分校

作物科学系

博士后

研究方向：

玉米籽粒发育调控;玉米环境适应机制;表观遗传修饰的生物学功能及机制

代表性研究成果：

1. Li Q^#, Yan J^#. Sustainable agriculture in the era of omics: knowledge-driven crop breeding. Genome Biol, 2020, 21(1):154

2. Xu J, Chen G, Hermanson PJ, Xu Q, Sun C, Chen W, Kan Q, Li M, Crisp PA, Yan J, Li L, Springer NM^#, Li Q^#. Population-level analysis reveals the widespread occurrence and phenotypic consequence of DNA methylation variation not tagged by genetic variation in maize. Genome Biol, 2019, 20:243

3. Li X, Chen L, Zhang Q, Sun Y, Li Q^#, Yan J^#. BRIF-Seq: Bisulfite-converted randomly integrated fragments sequencing at the single-cell level. Mol Plant, 2019, 12(3):438-446

4. Wang H, Xu S, Fan Y, Liu N, Zhan W, Liu H, Xiao Y, Li K, Pan Q, Li W, Deng M, Liu J, Jin M, Yang X, Li J, Li Q^#, Yan J^#. Beyond pathways: genetic dissection of tocopherol content in maize kernels by combining linkage and association analyses. Plant Biotechnol J, 2018, 16(8):1464-1475

5. Anderson SN, Zynda GJ, Song J, Han Z, Vaughn MW, Li Q^#, Springer NM^#. Subtle perturbations of the maize methylome reveal genes and transposons silenced by chromomethylase or RNA-Directed DNA methylation pathways. G3, 2018, 8(6):1921-1932

6. Liu J, Huang J, Guo H, Lan L, Wang H, Xu Y, Yang X, Li W, Tong H, Xiao Y, Pan Q, Qiao F, Raihan MS, Liu H, Zhang X, Yang N, Wang X, Deng M, Jin M, Zhao L, Luo X, Zhou Y, Li X, Zhan W, Liu N, Wang H, Chen G, Li Q^#, Yan J^#. The conserved and unique genetic architecture of kernel size and weight in maize and rice. Plant Physiology, 2017, 175(2):774-785

7. Li Q, Gent JI, Zynda G, Song J, Makarevitch I, Hirsch CD, Hirsch CN, Dawe RK, Madzima TF, McGinnis KM, Lisch D, Schmitz RJ, Vaughn MW, Springer NM. RNA-directed DNA methylation enforces boundaries between heterochromatin and euchromatin in the maize genome. PNAS, 2015, 112(47):14728-14733

8. Li Q*, Song J*, West PT, Zynda G, Eichten SR, Vaughn MW, Springer NM. Examining the causes and consequences of context-specific differential DNA methylation in maize. Plant Physiology, 2015, 168: 1262–1274

9. Li Q*, Suzuki M*, Wendt J, Patterson N, Eichten SR, Hermanson PJ, Green D, Jeddeloh J, Richmond T, Rosenbaum H, Burgess D, Springer NM, Greally JM. Post-conversion targeted capture of modified cytosines in mammalian and plant genomes. Nucleic Acids Research, 2015, gkv244

10. Li Q, Li Y, Moose SP, Hudson ME. Transposable elements, mRNA expression level and strand-specificity of small RNAs are associated with non-additive inheritance of gene expression in hybrid plants. BMC Plant Biology, 2015, 15:168

11. Li Q, Eichten SR, Hermanson PJ, Zaunbrecher VM, Song J, Wendt J, Rosenbaum H, Madzima TF, Sloan AE, Huang J, Burgess DL, Richmond TA, McGinnis KM, Meeley RB, Danilevskaya ON, Vaughn MW, Kaeppler SM, Jeddeloh JA, Springer NM. Genetic perturbation of the maize methylome. The Plant Cell, 2014, 26(12):4602-4616

12. Li Q, Eichten SR, Hermanson PJ, Springer NM. Inheritance patterns and stability of DNA methylation variation in maize near-isogenic lines. Genetics, 2014, 196: 667-676

13. West PT*, Li Q*, Ji L, Eichten SR, Song J, Vaughn MW, Schmitz RJ, Springer NM. Genomic distribution of H3K9me2 and DNA methylation in a maize genome. PLoS ONE, 2014, 9(8): e105267

14. Li Q*, Yang X*, Xu S*, Cai Y, Zhang D, Han Y, Li L, Zhang Z, Gao S, Li J, Yan J. Genome-wide association studies identified three independent polymorphisms associated with α-Tocopherol content in maize kernels. PLoS ONE, 2012, 7(5): e36807

15. Li Q, Li L, Yang X, Warburton ML, Bai G, Dai J, Li J, Yan J. Relationship, evolutionary fate and function of two maize co-orthologs of rice GW2 associated with kernel size and weight. BMC Plant Biology, 2010, 10:143

16. Li Q, Yang X, Bai G, Warburton ML, Mahuku G, Gore M, Dai J, Li J, Yan J. Cloning and characterization of a putative GS3 ortholog involved in maize kernel development. Theoretical and Applied Genetics, 2010, 120: 753-763

17. Li Q, Li L, Dai J, Li J, Yan J. Identification and characterization of CACTA transposable elements capturing gene fragments in maize. Chinese Science Bulletin, 2009, 54(4):642-651

18. Zhang M, Ma X, Wang C, Li Q, Meyers BC, Springer NM, Walbot V. CHH DNA methylation increases at 24-PHAS loci depend on 24-nt phased small interfering RNAs in maize meiotic anthers. New Phytol, 2021, 229: 2984–2997

19. Xu G, Lyu J, Li Q, Liu H, Wang D, Zhang M, Springer NM, Ross-Ibarra J, Yang J (2020) Evolutionary and functional genomics of DNA methylation in maize domestication and improvement. Nat Commun, 11(1):5539

20. Huang J, Lu G, Liu L, Raihan MS, Xu J, Jian L, Zhao L, Tran TM, Zhang Q, Liu J, Li W, Wei C, Braun DM, Li Q, Fernie AR, Jackson D, Yan J. The Kernel Size-Related Quantitative Trait Locus qKW9 Encodes a Pentatricopeptide Repeat Protein That Aaffects Photosynthesis and Grain Filling. Plant Physiol. 2020, 183(4):1696-1709

21. Xue W, Anderson SN, Wang X, Yang L, Crisp PA, Li Q, Noshay J, Albert PS, Birchler JA, Bilinski P, Stitzer MC, Ross-Ibarra J, Flint-Garcia S, Chen X, Springer NM, Doebley JF. Hybrid Decay: A transgenerational epigenetic decline in vigor and viability triggered in backcross populations of teosinte with maize. Genetics. 2019, 213(1):143-160

22. Zhang H, Wang X, Pan Q, Li P, Liu Y, Lu X, Zhong W, Li M, Han L, Li J, Wang P, Li D, Liu Y, Li Q, Yang F, Zhang YM, Wang G, Li L. QTG-Seq accelerates QTL fine mapping through QTL partitioning and whole-genome sequencing of bulked segregant samples. Mol Plant. 2019, 12(3):426-437

23. Chen L, Zhang P, Fan Y, Lu Q, Li Q, Yan J, Muehlbauer GJ, Schnable PS, Dai M, Li L. Circular RNAs mediated by transposons are associated with transcriptomic and phenotypic variation in maize. New Phytologist, 2018, 217(3): 1292-1306

24. Springer NM, Anderson SN, Andorf CM, Ahern KR, Bai F, Barad O, Barbazuk WB, Bass HW, Baruch K, Ben-Zvi G, Buckler ES, Bukowski R, Campbell MS, Cannon EKS, Chomet P, Dawe RK, Davenport R, Dooner HK, Du LH, Du C, Easterling KA, Gault C, Guan JC, Hunter CT, Jander G, Jiao Y, Koch KE, Kol G, Köllner TG, Kudo T, Li Q, Lu F, Mayfield-Jones D, Mei W, McCarty DR, Noshay JM, Portwood JL 2nd, Ronen G, Settles AM, Shem-Tov D, Shi J, Soifer I, Stein JC, Stitzer MC, Suzuki M, Vera DL, Vollbrecht E, Vrebalov JT, Ware D, Wei S, Wimalanathan K, Woodhouse MR, Xiong W, Brutnell TP. The maize W22 genome provides a foundation for functional genomics and transposon biology. Nat Genet, 2018, 50(9):1282-1288

25. Han Z, Crisp PA, Stelpflug S, Kaeppler SM, Li Q, Springer NM. Heritable epigenomic changes to the maize methylome resulting from tissue culture. Genetics. 2018, 209(4):983-995

26. Wicker T, Schulman AH, Tanskanen J, Spannagl M, Twardziok S, Mascher M, Springer NM, Li Q, Waugh R, Li C, Zhang G, Stein N, Mayer KFX, Gundlach H. The repetitive landscape of the 5100 Mbp barley genome. Mob DNA. 2017, 8:22

27. Niederhuth CE, Bewick AJ, Ji L, Alabady MS, Kim KD, Li Q, Rohr NA, Rambani A, Burke JM, Udall JA, Egesi C, Schmutz J, Grimwood J, Jackson SA, Springer NM, Schmitz RJ. Widespread natural variation of DNA methylation within angiosperms. Genome Biology, 2016, 17(1):194.

28. Springer NM, Lisch D, Li Q. Creating order from chaos: Epigenome dynamics in plants with complex genomes. Plant Cell, 2016, 28(2): 314-325.

29. Eichten SR, Briskine R, Song J, Li Q, Swanson-Wagner R, Hermanson PJ, Waters AJ, Starr E, West PT, Tiffin P, Myers CL, Vaughn MW, Springer NM. Epigenetic and genetic influences on DNA methylation variation in maize populations. The Plant Cell, 2013, 25(8), 2783-2797

30. Xu S, Zhang D, Cai Y, Zhou Y, Trushar S, Farhan A, Li Q, Li Z, Wang W, Li J, Yang X, Yan J. Dissecting tocopherols content in maize (Zea mays L.), using two segregating populations and high-density single nucleotide polymorphism markers. BMC Plant Biology, 2012, 12:201.

31. Li L, Li H, Li Q, Yang X, Zheng D, Warburton M, Chai Y, Zhang P, Guo Y, Yan J, Li J. An 11-bp insertion in Zea mays fatb reduces the palmitic acid content of fatty acids in maize grain. PLoS ONE, 2011, 6(9): e24699

32. Yan J, Kandianis CB, Harjes CE, Bai L, Kim EH, Yang X, Skinner DJ, Fu Z, Mitchell S, Li Q, Fernandez MG, Zaharieva M, Babu R, Fu Y, Palacios N, Li J, Dellapenna D, Brutnell T, Buckler ES, Warburton ML, Rocheford T. Rare genetic variation at CrtR-B1 increases β-carotene in maize grain. Nature Genetics, 2010, 42:322-327

33. Yang X, Yan J, Shah T, Warburton ML, Li Q, Li L, Gao Y, Chai Y, Fu Z, Zhou Y, Xu S, Bai G, Meng Y, Zheng Y, Li J. Genetic analysis and characterization of a new maize association mapping panel for quantitative trait loci dissection. Theoretical and Applied Genetics, 2010, 121:417–431

获得奖励：

1.2018年，国家青年项目

2.2017年，湖北省人才项目

主讲课程：

遗传学

研究生招生专业：

遗传学、生物化学与分子生物学、基因组学

联系方式：

电子邮箱：

qingli@mail.hzau.edu.cn

办公地点：

作物遗传改良国家重点实验室A214